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The GSSG-dependent oxidation of roGFP2 by fused PfGrx variants is two to three orders of magnitude faster than the oxidation by unfused PfGrx(SSG) variants and more than seven orders of magnitude faster than the uncatalyzed reaction with GSSG (Table 1)

For drug administration, rats in the IRI-AKI + CC and IRI-AKI + AICAR + CC groups received an intraperitoneal injection of CC (10 mg/kg) at 5.5 h after model establishment

A good plan respects that interdependence

PSEN1/2 mutations identified in Alzheimer patients affected the hypoxic response in mouse embryonic fibroblasts by regulating hypoxia inducible factor-1 (HIF-1), a driver of vulnerability to ferroptosis in cancer (Kaufmann et al., 2013